T15P (p.Thr15Pro) variant of ALPL (P05186)
T15P (p.Thr15Pro) in ALPL (P05186) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
T15P (p.Thr15Pro) variant details
- p.Thr15Pro
- gnomAD rs1241484434
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.52
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available