P26H (p.Pro26His) variant of ALPL (P05186)
P26H (p.Pro26His) in ALPL (P05186) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
P26H (p.Pro26His) variant details
- p.Pro26His
- cosmic curated COSV66379
- gnomAD rs1170372723
- Missense
- Variant Prioritization Score for Impact Estimate 0.797
- REVEL 0.81
- CADD 25.10
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available