E4* (p.Glu4Ter) variant of ALMS1 (Q8TCU4)

E4* (p.Glu4Ter) in ALMS1 (Q8TCU4) is a protein-truncating change. Clinical records from EBI and UniProt describe it as likely pathogenic. The record also includes variant effect predictions, population frequency data, and published literature.

E4* (p.Glu4Ter) variant details