R25L (p.Arg25Leu) variant of ALDH5A1 (P51649)
R25L (p.Arg25Leu) in ALDH5A1 (P51649) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
R25L (p.Arg25Leu) variant details
- p.Arg25Leu
- gnomAD 6-24495070-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.23
- MetaLR 0.12
- MetaSVM -0.99
- CADD 8.25
- PolyPhen-2 0.00
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available