R25H (p.Arg25His) variant of ALDH5A1 (P51649)
R25H (p.Arg25His) in ALDH5A1 (P51649) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R25H (p.Arg25His) variant details
- p.Arg25His
- TOPMed rs1457708018
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.20
- MetaLR 0.11
- MetaSVM -0.89
- CADD 10.70
- PolyPhen-2 0.21
- SIFT 0.06
- Population evidence available
- Structural context available