V25M (p.Val25Met) variant of ALDH2 (P05091)
V25M (p.Val25Met) in ALDH2 (P05091) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
V25M (p.Val25Met) variant details
- p.Val25Met
- TOPMed rs2068163983
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.21
- CADD 18.00
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the East Asian population (allele frequency 2.9e-05)
- Structural context available