L16F (p.Leu16Phe) variant of ALDH2 (P05091)
L16F (p.Leu16Phe) in ALDH2 (P05091) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L16F (p.Leu16Phe) variant details
- p.Leu16Phe
- ExAC rs755268259
- TOPMed rs755268259
- gnomAD rs755268259
- Missense
- Variant Prioritization Score for Impact Estimate 0.166
- REVEL 0.10
- CADD 3.20
- PolyPhen-2 0.00
- SIFT 0.94
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available