F8L (p.Phe8Leu) variant of ALDH2 (P05091)
F8L (p.Phe8Leu) in ALDH2 (P05091) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
F8L (p.Phe8Leu) variant details
- p.Phe8Leu
- TOPMed rs1210605825
- gnomAD rs1210605825
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.09
- CADD 9.20
- PolyPhen-2 0.00
- SIFT 0.79
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available