Y26F (p.Tyr26Phe) variant of AKT3 (Q9Y243)
Y26F (p.Tyr26Phe) in AKT3 (Q9Y243) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
Y26F (p.Tyr26Phe) variant details
- p.Tyr26Phe
- gnomAD rs1261943456
- Missense
- Variant Prioritization Score for Impact Estimate 0.608
- MetaLR 0.58
- MetaSVM 0.21
- CADD 25.80
- PolyPhen-2 0.97
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available