T122A (p.Thr122Ala) variant of AKT3 (Q9Y243)
T122A (p.Thr122Ala) in AKT3 (Q9Y243) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data.
T122A (p.Thr122Ala) variant details
- p.Thr122Ala
- ESP rs371339772
- ExAC rs371339772
- TOPMed rs371339772
- gnomAD rs371339772
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- MetaLR 0.05
- MetaSVM -1.07
- CADD 18.50
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 7.2e-05)