S136F (p.Ser136Phe) variant of AKT3 (Q9Y243)
S136F (p.Ser136Phe) in AKT3 (Q9Y243) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
S136F (p.Ser136Phe) variant details
- p.Ser136Phe
- cosmic curated COSV55630
- gnomAD rs1217463895
- Missense
- Variant Prioritization Score for Impact Estimate 0.579
- MetaLR 0.07
- MetaSVM -0.99
- CADD 24.20
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available