N127S (p.Asn127Ser) variant of AKT3 (Q9Y243)
N127S (p.Asn127Ser) in AKT3 (Q9Y243) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data.
N127S (p.Asn127Ser) variant details
- p.Asn127Ser
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- MetaLR 0.05
- MetaSVM -1.07
- CADD 17.40
- PolyPhen-2 0.00
- SIFT 0.09
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)