I128T (p.Ile128Thr) variant of AKT3 (Q9Y243)
I128T (p.Ile128Thr) in AKT3 (Q9Y243) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
I128T (p.Ile128Thr) variant details
- p.Ile128Thr
- cosmic curated COSV10956
- gnomAD rs1487348762
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- MetaLR 0.04
- MetaSVM -1.06
- CADD 20.20
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the East Asian population (allele frequency 5e-05)