I125T (p.Ile125Thr) variant of AKT3 (Q9Y243)
I125T (p.Ile125Thr) in AKT3 (Q9Y243) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data.
I125T (p.Ile125Thr) variant details
- p.Ile125Thr
- ExAC rs200534356
- gnomAD rs200534356
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- MetaLR 0.04
- MetaSVM -1.07
- CADD 19.90
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)