V74I (p.Val74Ile) variant of AKT2 (P31751)
V74I (p.Val74Ile) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
V74I (p.Val74Ile) variant details
- p.Val74Ile
- ExAC rs754309980
- TOPMed rs754309980
- gnomAD rs754309980
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.10
- CADD 14.90
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available