T72S (p.Thr72Ser) variant of AKT2 (P31751)
T72S (p.Thr72Ser) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
T72S (p.Thr72Ser) variant details
- p.Thr72Ser
- ExAC rs765768303
- gnomAD rs765768303
- Missense
- Variant Prioritization Score for Impact Estimate 0.612
- REVEL 0.51
- CADD 24.00
- PolyPhen-2 0.75
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available