T21S (p.Thr21Ser) variant of AKT2 (P31751)
T21S (p.Thr21Ser) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
T21S (p.Thr21Ser) variant details
- p.Thr21Ser
- Ensembl rs2145307230
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.22
- CADD 24.20
- PolyPhen-2 0.69
- SIFT 0.22
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available