S31N (p.Ser31Asn) variant of AKT2 (P31751)
S31N (p.Ser31Asn) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
S31N (p.Ser31Asn) variant details
- p.Ser31Asn
- ExAC rs779811637
- gnomAD rs779811637
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.10
- CADD 19.10
- PolyPhen-2 0.03
- SIFT 0.35
- Most common in the South Asian population (allele frequency 4.6e-05)
- Structural context available