R76C (p.Arg76Cys) variant of AKT2 (P31751)
R76C (p.Arg76Cys) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
R76C (p.Arg76Cys) variant details
- p.Arg76Cys
- Ensembl rs2145293731
- Missense
- Variant Prioritization Score for Impact Estimate 0.575
- REVEL 0.39
- CADD 31.00
- PolyPhen-2 0.82
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available