R41K (p.Arg41Lys) variant of AKT2 (P31751)
R41K (p.Arg41Lys) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
R41K (p.Arg41Lys) variant details
- p.Arg41Lys
- TOPMed rs1197293098
- gnomAD rs1197293098
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.07
- CADD 18.30
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available