R25W (p.Arg25Trp) variant of AKT2 (P31751)
R25W (p.Arg25Trp) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
R25W (p.Arg25Trp) variant details
- p.Arg25Trp
- Ensembl rs2145307119
- Missense
- Variant Prioritization Score for Impact Estimate 0.581
- REVEL 0.55
- CADD 28.20
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available