R25Q (p.Arg25Gln) variant of AKT2 (P31751)
R25Q (p.Arg25Gln) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
R25Q (p.Arg25Gln) variant details
- p.Arg25Gln
- cosmic curated COSV60908
- ExAC rs746989021
- gnomAD rs746989021
- Missense
- Variant Prioritization Score for Impact Estimate 0.576
- REVEL 0.41
- CADD 27.80
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available