R101L (p.Arg101Leu) variant of AKT2 (P31751)
R101L (p.Arg101Leu) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R101L (p.Arg101Leu) variant details
- p.Arg101Leu
- gnomAD rs968169579
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.22
- CADD 14.60
- PolyPhen-2 0.04
- SIFT 0.12
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available