P93L (p.Pro93Leu) variant of AKT2 (P31751)
P93L (p.Pro93Leu) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
P93L (p.Pro93Leu) variant details
- p.Pro93Leu
- cosmic curated COSV10732
- TOPMed rs965617770
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- REVEL 0.19
- CADD 25.70
- PolyPhen-2 0.02
- SIFT 0.25
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available