P68L (p.Pro68Leu) variant of AKT2 (P31751)
P68L (p.Pro68Leu) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
P68L (p.Pro68Leu) variant details
- p.Pro68Leu
- TOPMed rs1410236931
- gnomAD rs1410236931
- Missense
- Variant Prioritization Score for Impact Estimate 0.581
- REVEL 0.42
- CADD 28.10
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available