P51S (p.Pro51Ser) variant of AKT2 (P31751)
P51S (p.Pro51Ser) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
P51S (p.Pro51Ser) variant details
- p.Pro51Ser
- TOPMed rs201145928
- gnomAD rs201145928
- Missense
- Variant Prioritization Score for Impact Estimate 0.702
- REVEL 0.73
- CADD 24.90
- PolyPhen-2 0.98
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available