P51L (p.Pro51Leu) variant of AKT2 (P31751)
P51L (p.Pro51Leu) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
P51L (p.Pro51Leu) variant details
- p.Pro51Leu
- ExAC rs770250877
- TOPMed rs770250877
- gnomAD rs770250877
- Missense
- Variant Prioritization Score for Impact Estimate 0.69
- REVEL 0.61
- CADD 28.50
- PolyPhen-2 0.74
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available