P50A (p.Pro50Ala) variant of AKT2 (P31751)
P50A (p.Pro50Ala) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
P50A (p.Pro50Ala) variant details
- p.Pro50Ala
- 1000Genomes rs184042322
- ExAC rs184042322
- TOPMed rs184042322
- gnomAD rs184042322
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.11
- CADD 20.20
- PolyPhen-2 0.00
- SIFT 0.45
- Most common in the Latino/Admixed American population (allele frequency 8.9e-05)
- Structural context available