P24L (p.Pro24Leu) variant of AKT2 (P31751)
P24L (p.Pro24Leu) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
P24L (p.Pro24Leu) variant details
- p.Pro24Leu
- cosmic curated COSV10588
- gnomAD rs1272565080
- Missense
- Variant Prioritization Score for Impact Estimate 0.603
- REVEL 0.46
- CADD 28.80
- PolyPhen-2 0.92
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available