I19F (p.Ile19Phe) variant of AKT2 (P31751)
I19F (p.Ile19Phe) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
I19F (p.Ile19Phe) variant details
- p.Ile19Phe
- TOPMed rs1438443076
- gnomAD rs1438443076
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.39
- CADD 25.40
- PolyPhen-2 0.94
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available