G33S (p.Gly33Ser) variant of AKT2 (P31751)
G33S (p.Gly33Ser) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
G33S (p.Gly33Ser) variant details
- p.Gly33Ser
- cosmic curated COSV60909
- TOPMed rs1975585202
- Missense
- Variant Prioritization Score for Impact Estimate 0.564
- REVEL 0.47
- CADD 27.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available