E9K (p.Glu9Lys) variant of AKT2 (P31751)
E9K (p.Glu9Lys) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
E9K (p.Glu9Lys) variant details
- p.Glu9Lys
- ExAC rs748173515
- TOPMed rs748173515
- gnomAD rs748173515
- Missense
- Variant Prioritization Score for Impact Estimate 0.646
- REVEL 0.57
- CADD 25.00
- PolyPhen-2 0.25
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available