E85K (p.Glu85Lys) variant of AKT2 (P31751)
E85K (p.Glu85Lys) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
E85K (p.Glu85Lys) variant details
- p.Glu85Lys
- cosmic curated COSV60908
- TOPMed rs1393896368
- gnomAD rs1393896368
- Missense
- Variant Prioritization Score for Impact Estimate 0.808
- REVEL 0.81
- CADD 28.50
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available