E66K (p.Glu66Lys) variant of AKT2 (P31751)
E66K (p.Glu66Lys) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
E66K (p.Glu66Lys) variant details
- p.Glu66Lys
- ExAC rs747803532
- TOPMed rs747803532
- gnomAD rs747803532
- Missense
- Variant Prioritization Score for Impact Estimate 0.62
- REVEL 0.54
- CADD 22.90
- PolyPhen-2 0.08
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available