E66D (p.Glu66Asp) variant of AKT2 (P31751)
E66D (p.Glu66Asp) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
E66D (p.Glu66Asp) variant details
- p.Glu66Asp
- TOPMed rs1302715414
- gnomAD rs1302715414
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.17
- CADD 15.20
- PolyPhen-2 0.01
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available