D91Y (p.Asp91Tyr) variant of AKT2 (P31751)
D91Y (p.Asp91Tyr) in AKT2 (P31751) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
D91Y (p.Asp91Tyr) variant details
- p.Asp91Tyr
- gnomAD rs1205519703
- Missense
- Variant Prioritization Score for Impact Estimate 0.837
- REVEL 0.84
- CADD 33.00
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available