R41W (p.Arg41Trp) variant of AKT1 (P31749)
R41W (p.Arg41Trp) in AKT1 (P31749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
R41W (p.Arg41Trp) variant details
- p.Arg41Trp
- ExAC rs753765116
- gnomAD rs753765116
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- CADD 23.60
- PolyPhen-2 0.04
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available