K8R (p.Lys8Arg) variant of AKT1 (P31749)
K8R (p.Lys8Arg) in AKT1 (P31749) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
K8R (p.Lys8Arg) variant details
- p.Lys8Arg
- gnomAD rs1173631887
- Missense
- Variant Prioritization Score for Impact Estimate 0.589
- CADD 24.10
- PolyPhen-2 0.25
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available