R22G (p.Arg22Gly) variant of AIP (AH receptor-interacting protein)
R22G (p.Arg22Gly) in AIP (AH receptor-interacting protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
R22G (p.Arg22Gly) variant details
- p.Arg22Gly
- gnomAD 11-67483222-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.431
- REVEL 0.35
- MetaLR 0.56
- MetaSVM -0.45
- CADD 18.30
- PolyPhen-2 0.00
- SIFT 0.38
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available