L25V (p.Leu25Val) variant of AIP (AH receptor-interacting protein)
L25V (p.Leu25Val) in AIP (AH receptor-interacting protein) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes structural context.
L25V (p.Leu25Val) variant details
- p.Leu25Val
- rs777083581
- ClinGen CA381545844
- ClinVar RCV003680803
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.708
- AlphaMissense 0.27
- MetaLR 0.83
- MetaSVM 0.78
- SIFT 0.01
- MutPred 0.36
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available