G12A (p.Gly12Ala) variant of AIP (AH receptor-interacting protein)
G12A (p.Gly12Ala) in AIP (AH receptor-interacting protein) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes structural context.
G12A (p.Gly12Ala) variant details
- p.Gly12Ala
- rs1357679684
- ClinGen CA381545768
- ClinVar RCV003022066
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.826
- AlphaMissense 0.62
- MetaLR 0.86
- MetaSVM 0.89
- SIFT 0.00
- MutPred 0.74
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available