R77C (p.Arg77Cys) variant of AICDA (Q9GZX7)
R77C (p.Arg77Cys) in AICDA (Q9GZX7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
R77C (p.Arg77Cys) variant details
- p.Arg77Cys
- cosmic curated COSV10506
- ExAC rs757613881
- gnomAD rs757613881
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.42
- MetaLR 0.39
- MetaSVM -0.18
- CADD 31.00
- PolyPhen-2 0.93
- SIFT 0.04
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available