R63H (p.Arg63His) variant of AICDA (Q9GZX7)
R63H (p.Arg63His) in AICDA (Q9GZX7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
R63H (p.Arg63His) variant details
- p.Arg63His
- cosmic curated COSV57563
- ESP rs368910905
- ExAC rs368910905
- TOPMed rs368910905
- Missense
- Variant Prioritization Score for Impact Estimate 0.391
- REVEL 0.20
- MetaLR 0.16
- MetaSVM -0.90
- CADD 23.00
- PolyPhen-2 0.03
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available