R63C (p.Arg63Cys) variant of AICDA (Q9GZX7)
R63C (p.Arg63Cys) in AICDA (Q9GZX7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
R63C (p.Arg63Cys) variant details
- p.Arg63Cys
- ExAC rs753194739
- gnomAD rs753194739
- Missense
- Variant Prioritization Score for Impact Estimate 0.536
- REVEL 0.41
- MetaLR 0.35
- MetaSVM -0.33
- CADD 31.00
- PolyPhen-2 0.73
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available