R35K (p.Arg35Lys) variant of AICDA (Q9GZX7)
R35K (p.Arg35Lys) in AICDA (Q9GZX7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
R35K (p.Arg35Lys) variant details
- p.Arg35Lys
- gnomAD rs1490176772
- Missense
- Variant Prioritization Score for Impact Estimate 0.55
- REVEL 0.49
- MetaLR 0.53
- MetaSVM -0.20
- CADD 18.40
- PolyPhen-2 0.02
- SIFT 0.10
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available