F46L (p.Phe46Leu) variant of AICDA (Q9GZX7)
F46L (p.Phe46Leu) in AICDA (Q9GZX7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
F46L (p.Phe46Leu) variant details
- p.Phe46Leu
- ESP rs373878983
- ExAC rs373878983
- gnomAD rs373878983
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.45
- MetaLR 0.29
- MetaSVM -0.34
- CADD 13.40
- PolyPhen-2 0.99
- SIFT 0.32
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available