D71E (p.Asp71Glu) variant of AICDA (Q9GZX7)
D71E (p.Asp71Glu) in AICDA (Q9GZX7) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
D71E (p.Asp71Glu) variant details
- p.Asp71Glu
- NCI-TCGA Cosmic COSV5756
- cosmic curated COSV57564
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.27
- MetaLR 0.32
- MetaSVM -0.49
- CADD 23.20
- PolyPhen-2 0.78
- SIFT 0.07
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available