D67Y (p.Asp67Tyr) variant of AICDA (Q9GZX7)
D67Y (p.Asp67Tyr) in AICDA (Q9GZX7) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
D67Y (p.Asp67Tyr) variant details
- p.Asp67Tyr
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.31
- MetaLR 0.13
- MetaSVM -0.88
- CADD 17.80
- PolyPhen-2 0.08
- SIFT 1.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available