L25L (p.Leu25Leu) variant of AGXT (P21549)
L25L (p.Leu25Leu) in AGXT (P21549) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L25L (p.Leu25Leu) variant details
- p.Leu25Leu
- gnomAD 2-240868940-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.259
- CADD 1.25
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- AGXT complementation assay *1 B: score 0.283
- Literature evidence available