W21* (p.Trp21Ter) variant of AGTRAP (Q6RW13)

Name: AGTRAP W21* (p.Trp21Ter) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-10-06
License: https://catvariant.com/terms-of-use

W21* (p.Trp21Ter) in AGTRAP (Q6RW13) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.90 / 1. The record also includes population frequency data and structural context.

W21* (p.Trp21Ter) variant details

p.Trp21Ter
NCI-TCGA Cosmic COSV5866
cosmic curated COSV58669
TOPMed rs1570346569
Variant assessed as somatic; high impact.
Stop Gained
Variant Prioritization Score for Impact Estimate 0.902
CADD 45.00
SIFT 0.16
UniProt: Variant assessed as somatic; high impact.
Most common in the HGDP:OROQEN population (allele frequency 0.062)
Structural context available